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Recurrent and back Y-SNP mutations
Topic Started: Mar 18 2007, 02:06:48 AM (515 Views)
black man
The Right Hand
[ *  *  * ]
recurrent mutations mentioned in Butler's paper:

marker: haplogroups:
M37 I1b, R1b
M64 D2, R1a1 (comment)
M108 B2a, B2b
M116 D2b, E3a (comment)
M165 E3a, E3b
MSY2 B2, O1
12f2 D2, J

more:

P37: D2, I1b (comment)
P41: D2, I1b1 (comment)
IMS-JST002611: O3, K(xN1,O2b,O3) Inagaki et al. 2002

back mutations:

P25 within R1b (see paper by Adams et al.)
M201 within G2 (see Whit Athey project news)

unsolved case:

Line1 was reported by Xue et al. and then by Nonaka et al. to be a back mutation. However, when you compare their data sets with that of Huang et al., you might get the idea that Line1 is a recurrent mutation. Apparently, Nonaka et al. and Xue et al. place the Line1 mutation within different sublineages when the data of Huang et al. are correct. The main problem seems to be that Nonaka et al. didn't test M7 and Xue et al. didn't use the new Japanese marker 021354. However, Huang et al. used both of them, which does nevertheless not change the fact that the samples of the three research teams were different ones...So far, it only seems to be clear that the LINE1 element is integrated into the repetitive alphoid satellite array and is therefore more prone that e.g. the 021354 point mutation to mutate back (or to recur). Information about the other markers wasn't published, to my knowledge.

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See p. 11 in Butler's Recent Developments in Y-Short Tandem Repeat and Y-Single Nucleotide Polymorphism Analysis (2003) and Kercher's SNP names and information table.
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